Congenital portosystemic shunts

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منابع مشابه

Imaging of Congenital Portosystemic Shunts

T he normal portal vascular system transports venous blood from the stomach, intestines, spleen, and pancreas to the hepatic sinusoids and ultimately the hepatic veins and caudal vena cava. Portosystemic shunting (PSS) occurs when abnormal vascular connections occur between the portal and systemic venous systems, bypassing the liver. This can be acquired secondary to portal hypertension arising...

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Portosystemic shunts in dogs and cats: laboratory diagnosis of congenital portosystemic shunts

The most frequent laboratory abnormalities in patients with congenital portosystemic shunts (CPSS) are microcytosis, hypoglycemia, hypoalbuminemia, hypoproteinemia, increased liver enzyme activities, decreased blood urea nitrogen (BUN) and urate crystalluria. The microcytosis is probably due to impaired iron transport. Hypoglycemia, hypoalbuminemia, hypoproteinemia and decreased BUN are partly ...

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Portosystemic shunts in dogs and cats: definition, epidemiology and clinical signs of congenital portosystemic shunts

Congenital portosystemic shunts (CPSS) are hepatic vascular anomalies which can affect any breed of dog or cat. Extrahepatic CPSS are most commonly observed in cats and small dogs, whereas intrahepatic CPSS are more likely to affect large breed dogs. A hereditary basis has been observed in some dog breeds. Affected animals are usually presented at young age with a variety of neurological, gastr...

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Congenital portosystemic shunts in children: recognition, evaluation, and management.

Congenital portosystemic shunts are present in one in 30,000 children. Among the associated risks of severe complications are neonatal cholestasis, benign and malignant liver tumors, hepatopulmonary syndrome, portopulmonary hypertension, and encephalopathy. They can be detected on prenatal ultrasonograms, during the investigation of a positive galactosemia screening test in neonates or of a com...

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The C57BL/6J Mouse Exhibits Sporadic Congenital Portosystemic Shunts

C57BL/6 mice are the most widely used strain of laboratory mice. Using in vivo proton Magnetic Resonance Spectroscopy ((1)H MRS), we have repeatedly observed an abnormal neurochemical profile in the brains of both wild-type and genetically modified mice derived from the C57BL/6J strain, consisting of a several fold increase in cerebral glutamine and two fold decrease in myo-inositol. This strik...

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ژورنال

عنوان ژورنال: Clinics and Research in Hepatology and Gastroenterology

سال: 2020

ISSN: 2210-7401

DOI: 10.1016/j.clinre.2020.03.004